Pharmacologic Alternatives to BZRAs
The third group of treatments consists of non-benzodiazepine pharmacological agents (note: Not z-drugs, since they have mechanisms of action at the GABA receptor similar to benzodiazepines). These include:
- Adrenergic inhibiting agents
- Mono-amine agents
- Serotonin receptor agents
- Anti-psychotic medications
- Sodium channel blockers
- Calcium channel modulators
- Glutamine system agents
- Hormones
- Plant-based medicines, including CBD