On-Label Uses of Benzodiazepines and non-Benzodiazepine Hypnotics (Z-Drugs) Each pharmaceutical is required to have a label (also called Prescribing Information) which lists, among other things,… Read More »On and Off Label Uses
Prescription Guidelines Summary: Most people will become dependent after 6 weeks continuous use. Only 30% of benzodiazepine dependent people ever get off them completely. While many… Read More »Prescription Guidelines
BZs, Z-Drugs Cost/Benefit and Medical Decision-Making Medical providers are expected to address medical problems in a stepwise process, which includes: taking a patient history, performing… Read More »BZs, Z-Drugs Cost/Benefit and Medical Decision-Making
Benzodiazepines and Other Drugs Benzodiazepines and Z-drugs act as central nervous system (CNS) depressants. Several other drugs (e.g., carisoprodol (Soma®), alcohol, opioids, tricyclic antidepressants) are… Read More »Benzodiazepines and Other Drugs
How do Benzodiazepines and Z-Drugs Work? Gamma-aminobutyric acid (GABA) is the major inhibitory neurochemical of the central nervous system and acts by binding to a… Read More »How do Benzodiazepines and Z-Drugs Work?
Z-Drugs Which Drugs are “Z-drugs” or “Nonbenzodiazepines”? The Z-drugs are typically prescribed for insomnia. In addition to carrying the same risks of physiological dependence and… Read More »Z-Drugs
What Are Benzodiazepines and Z-drugs? Benzodiazepines, also known as BZs or benzos, are commonly prescribed for anxiety, insomnia, muscle tension and a variety of other… Read More »What Are Benzodiazepines and Z-drugs?
A good model for BZRAs may be found in the progression of the latest in several waves of opioid crises in the United States. Opioids… Read More »Lessons from the Opioids and Fluoroquinolones
Legislature-Based Reforms New Jersey In 2022, the New Jersey state legislature introduced a bill that could become the standard for legislation that regulates the prescription… Read More »BZD Reform History
Promotion of benzodiazepine best practices happens at many levels, ranging from the guidelines and policies of medical societies and state medical boards through state and… Read More »Regulatory Reform